Effects of an environmentally relevant mixture of organophosphate esters on the phenotype and function of HepG2 liver cells.

 

 

Associations Between Gestational Polybrominated Diphenyl Ether (PBDE) Serum Concentrations and Child Sleep Outcomes from Ages 2 to 8 Years.

 

Organophosphate Flame Retardants Disrupt Neurodevelopmental Gene Networks with Autism-Relevant Features: A Multi-Omics Study in Rats.

 

 

Decabromodiphenyl ethane induces intrauterine growth restriction by suppressing placental angiogenesis via TWIST2/NAT10-mediated ac4C-dependent TGF-β1 mRNA stabilization.

 

Kinetics release of melamine phosphate from polyurethane foam: Implications for human exposure and environmental stability. 

 

Associations between brominated and organophosphate flame retardant levels and inflammatory biomarkers in maternal blood, cord blood, and placental tissue at mid-gestation.

 

Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate.

 

 

Developmental neurotoxicity of organophosphate flame retardants (OPFRs): risks to human health and ecosystems. 

  

Halogenated flame retardants in the sediments of the lower Great Lakes and region-wide discoveries. [Halogenated FRs in the Great Lakes sediment amount to approximately 420 tonnes.]

 

Tetrabromophthalate bis(2-ethylhexyl) ester (TBPH) exposure induces renal inflammation injury by activating MAVS-IRF3 signaling pathway in vitro and in vivo models.

 

 

Prenatal Persistent Exposure to Organophosphate Esters and Early Childhood Brain Development: A Longitudinal Analysis.

  

PBDE Concentrations in Wastes from Construction and Demolition, Soft Furnishings, and End-of-Life Vehicles in Brazil. 

 

Mitochondria Under Fire: Toxicological Mechanisms of Brominated Flame Retardants. [Conclusion: This underscores the urgent need for a paradigm shift toward mechanism-based risk assessment to prevent future cycles of hazardous chemical replacements and to guide the design of genuinely safer alternatives.]

 

Brominated organic compounds in leachate across China: Occurrence and molecular variations. 

 

Chemical disruption of placental thyroid hormone signalling: a systematic review that highlights sex-specific effects. 

 

A Critical Review of Occurrence and Emission of Brominated Flame Retardants in Indoor Consumer Products.

 

Human exposure to organophosphate esters (OPEs): A meta-analytic review of levels and distribution.

 

Sex-specific DNA methylation changes in placental thyroid hormone regulatory genes following prenatal exposure to flame retardants.

 

Transcriptomic and functional analysis of triphenyl phosphate exposure in prostate cancer progression.

 

Tris(2-chloroethyl) phosphate alters gut microbiota and hepatic metabolism in freshwater turtles at environmentally relevant concentrations.

 

Dermal Exposure to Organophosphorus Compounds in Home Video Game Controllers.

 

Assessing the solubility, chemical stability and ecotoxicology of an emerging non-halogenated flame retardant, melamine cyanurate, against a prevalent halogenated congener, tetrabromophthalic anhydride.

 

Embryonic Exposure to TPhP Elicits Osteotoxicity via Metabolic Disruption in Oryzias latipes.

 

Prenatal exposure to organophosphorus flame retardants and birth outcomes: A cross-sectional study in an e-waste area in China. 

 

The significance of organophosphate flame retardants in patients with esophageal squamous cell carcinoma.

 

Brominated Flame Retardants Exposure Promotes the Formation of Atherosclerotic Plaque in Aortic Roots of ApoE -/- Mice by Increasing Macrophage Recruitment and Foam Cell Formation.

 

Tris (1,3-dichloro-2-propyl) phosphate (TDCPP) aggravates Parkinson's disease neurotoxicity through ferroptosis-related oxidative stress and neuroinflammation.

 

Exposure to tris(2,4-di-tert-butylphenyl) phosphate during adolescence induces testicular toxicity in mice: Autophagy-apoptosis interplay.

 

The association between exposure to brominated flame retardants (BFRs) and arthritis, osteoarthritis, and rheumatoid arthritis: a cross-sectional study.

 

Environmental and Food Safety Assessment of Pre-Harvest Activities in Local Small-Scale Fruit and Vegetable Farms in Northwest Portugal: Hazard Identification and Compliance with Good Agricultural Practices (GAPs).[Phosphorus flame retardants (PFRs), particularly tris(2-butoxyethyl) phosphate (TBEP), were detected in all food and soil samples.]

 

Endocrine disruption of Triphenyl Phosphate via VIT-2 in Caenorhabditis elegans: A comparative analysis with estradiol and 4-hydroxytamoxifen. 

 

Prenatal exposure to organophosphate ester flame retardants and behavioral outcomes in early childhood in the Environmental influences on Child Health Outcomes (ECHO) cohort.

 

Chronic Exposure to Environmentally Relevant Doses of Triphenyl Phosphate Induces Anxiety- and Depression-Like Behaviors in Mice via the Gut-Brain Axis.

  

Epigenome-wide association study of gestational exposure to organophosphate esters and replacement brominated flame retardants with newborn DNA methylation.

 

Do polybrominated diphenyl ethers cause adverse effects in the freshwater bioindicator zebra mussel (Dreissena polymorpha Pallas, 1771)? An acute and subchronic biomarker assessment.

 

Associations of urinary organophosphate ester metabolites with bone mineral density in U.S. children and adolescents aged 8-19 years: a cross-sectional study based on NHANES 2011-2018.

 

Children's exposure risk toward brominated flame retardants and organophosphate esters during preschool attendance and potential contamination sources. [Swedish study]

 

Exposure to organophosphate ester flame retardants and plasticizers during pregnancy and autism-related outcomes in the ECHO Cohort. [Prenatal exposure to OPEs, specifically BCPP and BBOEP (metabolites of TCPP & TBOEP) , may be associated with higher risk of autism diagnosis and related traits in childhood]

 

Seasonal variation and human exposure characteristics of PBDEs in indoor dust, airborne particles and vapor phase in office environments.

 

Effects of global treaties on commercial chemicals widely used as additives: a meta-analysis of historical measurements of polybrominated diphenyl ethers [Important paper published in the Lancet Planetary Health but not listed on PUBMED. The study highlights the need for more cautious and stringent chemical regulations and a unified global monitoring and management framework in the future, to better regulate commercial additives.

 

Environmental Levels of Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) Cause Thyroid Toxicity and Early Carcinogenic Signals in Juvenile Fish. 

 

Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line.

 

Size Distribution and Gas/Particle Partitioning of Organophosphorus Flame Retardants in Indoor and Outdoor Air of Garment Factories.

 

Effects of global treaties on commercial chemicals widely used as additives: a meta-analysis of historical measurements of polybrominated diphenyl ethers. 

 

Transfer of Chlorinated Organophosphate Esters from Furniture Fabric to Indoor Dust via Direct Contact [Not yet listed on PUBMED]

 

Environmental and Food Safety Assessment of Pre-Harvest Activities in Local Small-Scale Fruit and Vegetable Farms in Northwest Portugal: Hazard Identification and Compliance with Good Agricultural Practices (GAPs). [Phosphorus flame retardants (PFRs), particularly tris(2-butoxyethyl) phosphate (TBEP), were detected in all food and soil samples.]

 

Intersecting circular economy and child health: A scoping review of legacy brominated flame retardants in plastic childcare products and toys.

 

Association between exposure to brominated flame retardants (BFRs) and blood lipid profiles in American adults: a cross-sectional study. 

 

Environmental concentrations of TCEP and TDCIPP induce dysbiosis of gut microbiotal and metabolism in the honeybee (Apis mellifera L.). 

 

Associations between brominated flame retardants, including polybrominated diphenyl ethers, and immune responses among women in the California Teachers Study.

 

Nationwide investigation on organophosphate esters and di-esters in raw grains from China: Distribution, sources, and implications for risk assessment.

 

Are Sleeping Children Exposed to Plasticizers, Flame Retardants, and UV-Filters from Their Mattresses? 

 

Multigenerational ecotoxicity of tris(2-butoxyethyl) phosphate to the tropical water flea Ceriodaphnia cornuta and probabilistic ecological risk assessment in freshwater environments.

 

Gestational PBDE concentrations and executive function in adolescents with self- and caregiver-report: The HOME study.

 

Extremely high levels of PBDEs in children’s toys from European markets: causes and implications for the circular economy

 

Phosphate Flame Retardants and Plasticizers and Their Association with Reproductive and Steroid Hormone Levels among Peripubertal-Aged Children: The Hokkaido Birth Cohort Study.

 

Decabromodiphenyl ethane exposure-mediated mitochondrial dysfunction drives oxeiptosis in placental trophoblasts and induces fetal growth restriction.

 

Associations between exposure to brominated flame retardants and hyperlipidemia risk in U.S. Adults. 

 

Biogeochemical Controls on Latitudinal (42°N to 70°S) and Depth Distribution of Organophosphate Esters in the Atlantic and Southern Oceans. [Very noteworthy showing the ubiquity of OPE contamination in the Atlantic ocean particularly TCPP]

 

High levels of flame retardants in vehicle dust indicate ongoing use of brominated and organophosphate flame retardants in vehicle interiors.

 

Decabromodiphenyl ethane exposure-mediated mitochondrial dysfunction drives oxeiptosis in placental trophoblasts and induces fetal growth restriction. [Note: this is the replacement chemical for decaBDE]

 

Developmental Immunotoxicity Study of Tris(chloropropyl) phosphate (TCPP) in Hsd:Sprague Dawley SD Rats Exposed Through Dosed Feed.

High-Throughput Zebrafish Screening Reveals Cardiotoxic Effects of Organophosphate Flame Retardants. 

Maternal organophosphate esters and sex steroid hormones in mid-pregnancy.

 

Effects of organophosphate esters on thyroid function during pregnancy: Risk of endocrine disruptors during early- and mid-pregnancy.

 

Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.

  

Association between exposure to brominated flame retardants and atherosclerosis: Evidence for inflammatory status as a potential mediator.

  

Association between brominated flame retardants and heart failure in U.S. adults: A cross-sectional analysis of national health and nutrition examination survey 2005-2016.

 

Effects of decabromodiphenyl ethane (DBDPE) exposure on soil microbial community: Nitrogen cycle, microbial defense and repair and antibiotic resistance genes transfer.

 

Pregnancy-related anxiety modifies the effects of maternal exposure to organophosphate esters on preschoolers' behavioral development.

 

Organophosphate Esters, Sperm Mitochondrial DNA Copy Number, and Semen Quality: A Longitudinal Study with Repeated Measurements.

 

Changes in molecular biomarkers of neurotoxicity in newborns following prenatal exposure to organophosphate compounds.

 

Ecotoxicological responses of marine fish to the organophosphate flame-retardant tris (2-chloroisopropyl) phosphate (TCPP) dietary exposure: Juvenile gilthead seabream (Sparus aurata) as a case study.

 

Association between the exposure to brominated flame retardants and psoriasis risk among U.S. adults: A population-based study.